« 2012年9月 | トップページ | 2012年11月 »


超人のジャーナリスト・アイ 150 ニューヨークにハリケーン襲来

ニューヨークにハリケーン襲来。下記はニューヨーク タイムズ電子版最新号からの転載。


Storm Slams Ashore and Disrupts Millions of Lives

The mammoth and merciless storm made landfall near Atlantic City around 8 p.m., with maximum sustained winds of about 80 miles per hour, the National Hurricane Center said. That was shortly after the center had reclassified the storm as a post-tropical cyclone, a scientific renaming that had no bearing on the powerful winds, driving rains and life-threatening storm surge expected to accompany its push onto land.

20121030_hp_stormslidex6sehplargev3The storm had unexpectedly picked up speed as it roared over the Atlantic Ocean on a slate-gray day and went on to paralyze life for millions of people in more than a half-dozen states, with extensive evacuations that turned shorefront neighborhoods into ghost towns. Even the superintendent of the Statue of Liberty left to ride out the storm at his mother’s house in New Jersey; he said the statue itself was “high and dry,” but his house in the shadow of the torch was not.

The wind-driven rain lashed sea walls and protective barriers in places like Atlantic City, where the Boardwalk was damaged as water forced its way inland. Foam was spitting, and the sand gave in to the waves along the beach at Sandy Hook, N.J., at the entrance to New York Harbor. Water was thigh-high on the streets in Sea Bright, N.J., a three-mile sand-sliver of a town where the ocean joined the Shrewsbury River.

“It’s the worst I’ve seen,” said David Arnold, watching the storm from his longtime home in Long Branch, N.J. “The ocean is in the road, there are trees down everywhere. I’ve never seen it this bad.”

The police said a tree fell on a house in Queens shortly after 7 p.m., killing a 30-year-old man. In Manhattan a few hours earlier, a construction crane atop one of the tallest buildings in the city came loose and dangled 80 stories over West 57th Street, across the street from Carnegie Hall.

Soon power was going out and water was rushing in. Waves topped the sea wall in the financial district in Manhattan, sending cars floating downstream. West Street, along the western edge of Lower Manhattan, looked like a river. The Brooklyn-Battery Tunnel, known officially as the Hugh L. Carey Tunnel in memory of a former governor, flooded hours after Gov. Andrew M. Cuomo of New York ordered it closed to traffic.

“We could be fishing out our windows tomorrow,” said Garnett Wilcher, a barber who lives in the Hammells Houses, a block from the ocean in the Rockaways in Queens. Still, he said he felt safe at home. Pointing to neighboring apartment houses in the city-run housing project, he said, “We got these buildings for jetties.”

Hurricane-force winds extended up to 175 miles from the center of the storm; tropical-storm-force winds spread out 485 miles from the center. Forecasters said tropical-storm-force winds could stretch all the way north to Canada and all the way west to the Great Lakes. Snow was expected in some states, with blizzard warnings issued for mountainous stretches of Maryland, Virginia and West Virginia.

Businesses and schools were closed; roads, bridges and tunnels were closed; and more than 13,000 airline flights were canceled. Even the Erie Canal was shut down.

Subways were shut down from Boston to Washington, as were Amtrak and the commuter rail lines. About 1,000 flights were canceled at each of the three major airports in the New York City area. Philadelphia International Airport had 1,200 canceled flights, according to FlightAware, a data provider in Houston.

A replica of the H.M.S. Bounty, a tall ship built for the 1962 movie “Mutiny on the Bounty” starring Marlon Brando and used in the recent “Pirates of the Caribbean” series, sank off the North Carolina coast. The Coast Guard said the 180-foot three-masted ship went down near the Outer Banks after being battered by 18-foot-high seas and thrashed by 40-m.p.h. winds. The body of one crew member, Claudene Christian, 42, was recovered. Another crew member remained missing.

Delaware banned cars and trucks from state roadways for other than “essential personnel.”
(Page 2 of 2)

“The most important thing right now is for people to use common sense,” Gov. Jack Markell said. “We didn’t want people out on the road going to work and not being able to get home again.”

The storm knocked out power to hundreds of thousands of homes, stores and office buildings. Consolidated Edison said 68,700 customers had lost power — 21,800 in Westchester County, 18,500 on Staten Island and 18,200 in Queens. In New Jersey, the Public Service Electric and Gas Company said the storm had knocked out power to 36,000 customers. In Connecticut, nearly 70,000 people had lost electricity, utility officials reported. Con Edison, fearing damage to its electrical equipment, shut down power pre-emptively in sections of Lower Manhattan — and then an unplanned failure knocked out power to most of Manhattan below Midtown, about 250,000 customers.

President Obama, who returned to the White House and met with top advisers, said the storm would disrupt the rhythms of daily life in the states it hit. “Transportation is going to be tied up for a long time,” he said, adding that besides flooding, there would probably be widespread power failures. He said utility companies had lined up crews to begin making repairs. But he cautioned that it could be slow going.

“The fact is, a lot of these emergency crews are not going to get into position to start restoring power until some of these winds die down,” the president said. He added, “That may take several days.”

Forecasters attributed the power of the storm to a convergence of weather systems. As the hurricane swirled north in the Atlantic and then pivoted toward land, a wintry storm was heading toward it from the west, and cold air was blowing south from the Arctic. The hurricane left more than 60 people dead in the Caribbean before it began crawling toward the Northeast.

“The days ahead are going to be very difficult, Gov. Martin O’Malley of Maryland said. “There will be people who die and are killed in this storm,” he said.

Alex Sosnowski, a senior meteorologist with AccuWeather, said potentially damaging winds would continue on Tuesday from Illinois to the Carolinas — and as far north as Maine — as the storm barreled toward the eastern Great Lakes.

Mr. Cuomo, who ordered many of the most heavily used bridges and tunnels in New York City closed, warned that the surge from Hurricane Sandy could go two feet higher than that associated with Tropical Storm Irene last year. The PATH system, buses and the Staten Island Ferry system were also suspended.

Joseph J. Lhota, the chairman and chief executive of the Metropolitan Transportation Authority, said he expected to restore at least some service about 12 hours after the storm ended. But he warned that the city could be without mass transit for as many as two workdays.

The storm headed toward land with weather that was episodic: a strong gust of wind one minute, then mist. More wind. Thin sheets of rain dancing down the street. Then, for a moment, nothing. The sky lightened. Then another blast of rain. Then more wind.

The day brought a giddiness to schoolchildren who had the day off and to grown-ups who were fascinated by the rough, rising water. Some went surfing, discounting the danger. Felquin Piedra, 38, rode his Jet Ski from Queens to Lower Manhattan.

“I love the waves,” Mr. Piedra yelled from New York Harbor. “The water is warm. I’ve jumped in several times.”

But even when landfall was still hours away, there was no holding back the advance guard of the storm — fast-moving bands of rain and punishing winds.

It added up to devastation. Driving through places like Pompton Plains, N.J., late Monday afternoon was like an X-Games contest for drivers. They had to do tree-limb slaloms on side streets and gunned their engines anxiously as they passed wind funnels of leaves swirling on highways.

On City Island, off the Bronx mainland, Cheryl Brinker sprayed “Sandy Stay Away” on her boarded-up art studio, expanding a collage she started during Tropical Storm Irene last year. But by midafternoon, nearby Ditmars Street was under as much as five feet of water and Steve Van Wickler said the water had cracked the cement in his cellar. “It’s like a little river running in my basement,” he said. “There are cracks and leaks everywhere.”

In some places, caravans of power-company trucks traveled largely empty roads; Public Service Electric and Gas said that 600 line workers and 526 tree workers had arrived from across the country, but could not start the repairs and cleanup until the wind had subsided, perhaps not until Wednesday.

They will see a landscape that, in many places, was remade by the storm. In Montauk, at the end of Long Island, a 50-seat restaurant broke in half. Half of the building floated away and broke into pieces on the beach.

The 110-foot-tall lighthouse at Montauk Point — the oldest in the state, opened in 1796 — shuddered in the storm despite walls that are six feet thick at the base. The lighthouse keeper, Marge Winski, said she had never felt anything like that in 26 years on the job.

“I went up in tower and it was vibrating, it was shaking,” she said. “I got out of it real quick. I’ve been here through hurricanes, and nor’easters, but nothing this bad.”

追記。ニューヨークにいる知人の昨日のメールによると、地下鉄は一部復旧、いくつかの路線も翌日までには乗れるようになるらしい。便利な地下鉄など交通機関が遮断されると身動きが取れないと嘆いていた(2012年11月1日 記)。


20121028_142822_2 Cazjsm37_2

追記3。アメリカ北東部を襲ったハリケーン「サンディ」による死者は、88人とCNN。大統領選も終盤、オバマ現職大統領がやや優勢らしい。今回のハリケーン対策が吉とでるか推移を見守りたい(2012.11.2 記)


クロカル超人の面白読書 96 最近読みかけの本など 続


20121020155536_00001_34.『日本人のための日本語文法入門』原沢伊都夫著 講談社新書 2012

5.雑誌『文学』2012年7-8月号 《特集》翻訳の創造力

6.『100年前の日本語ー書きことばが揺れた時代』今野真二著 岩波新書 2012.9
明治時代の日本語を文献などで丹念に読み込み、〈日本語の揺れ〉を探る好著。第5章 辞書の100年ー辞書を通じてみた日本語の変化、英和辞典の訳語他が興味大。

7.『みみずく偏書記』由良君美著 筑摩文庫 2012.5


クロカル超人の面白読書 96 最近読みかけの本など

昨日橋下徹大阪市長が週刊朝日に自分の出自などを暴かれたことに噛みつき、朝日新聞、朝日放送など朝日系列の取材を拒否すると発表。その俎上に登った記事は「ハシシタ 奴の本性」というタイトルでノンフィクション作家の佐野眞一+週刊朝日取材班が書いている。緊急連載もの。同じように週刊文春も橋下市長の記事を連載し始めた。政治などに疎い筆者の弁は保守的改革者のようであることだが、何を考え抜いて行動しているかがさっぱり解らない、テレビタレント的視聴率に勝てればいいような、よくいわれている大衆迎合的政治屋ポピュリストだろうか・・・。


1.『東電OL殺人事件』佐野眞一著 講談社文庫 初版 2003
ネパール人コビンタの無罪をずっと言い続けた著者の説得力のあるノンフィクション。処女作『旅する巨人ー宮本常 一と渋沢敬三』は未読、どちらの人物も興味あるので図書館から借り出して読んでみるつもり。

2.『福島原発 どうする日本の原発政策』安斎育郎著 かもがわ出版 2011

3.『白い沈黙』ジャスティン・エークマン著澤村灌訳 講談社文庫 1998


クロカル超人が行く 168 横須賀『よこすか海軍カレー館(魚藍亭)




クロカル超人が行く 169 久里浜「はなの国」

うす紅の秋桜が秋の日の 日溜まりに揺れている・・・・・・。






クロカル超人が行く 167 町田・仲見世カレーの店『アサノ』


Tokyo the greatest curry と書かれた文字の脇の棚にはキッチュっぽい置物がズラリ、何だかノスタルジーを感じさせる店だ。客が引けた後二代目店主とも多少話が出来た。今日は昼間が忙しかったので、材料の残りがあまりないためいつもの閉店時間より早めに店仕舞いすると。嬉しい話である。




2012年ノーベル生理学・医学賞発表 山中伸弥京大教授とイギリスのゴードンケンブリッジ大名誉教授に


追記。ノーベル生理学・医学賞発表直後の山中伸弥京大教授の記者会見の模様や山中教授自身がテレビに生出演した模様が放送された。受賞発表の知らせは家で電気洗濯機の修理中に携帯電話で受けた由。英語でだったと。この研究は難病の方々の治療薬として期待できるので早く実用化に漕ぎつけたいと。また、一緒に携わってきた多くの研究者仲間たちやこのプロジェクトを支援してくれている国に感謝申し上げると同時に、責任の重大さを感じていると飽くまで謙遜さを忘れない。iPS細胞研究が本格的に注目されてまだ6年、異例の受賞であることは間違いない。スポーツは好きらしく、柔道、マラソン、ゴルフ他をこなす体育会系の顔も。また酒豪とも。まだ50才、表情がいい。日本に元気をくれた(2012月10月9日 記)。



The Nobel Prize in Physiology or Medicine 2012
John B. Gurdon, Shinya Yamanaka
Press Release
The Nobel Assembly at Karolinska Institutet has today decided to award
The Nobel Prize in Physiology or Medicine 2012
jointly to
John B. Gurdon and Shinya Yamanaka
for the discovery that mature cells can be reprogrammed
to become pluripotent


The Nobel Prize recognizes two scientists who discovered that mature, specialised cells can be reprogrammed to become immature cells capable of developing into all tissues of the body. Their findings have revolutionised our understanding of how cells and organisms develop.

John B. Gurdon discovered in 1962 that the specialisation of cells is reversible. In a classic experiment, he replaced the immature cell nucleus in an egg cell of a frog with the nucleus from a mature intestinal cell. This modified egg cell developed into a normal tadpole. The DNA of the mature cell still had all the information needed to develop all cells in the frog.

Shinya Yamanaka discovered more than 40 years later, in 2006, how intact mature cells in mice could be reprogrammed to become immature stem cells. Surprisingly, by introducing only a few genes, he could reprogram mature cells to become pluripotent stem cells, i.e. immature cells that are able to develop into all types of cells in the body.

These groundbreaking discoveries have completely changed our view of the development and cellular specialisation. We now understand that the mature cell does not have to be confined forever to its specialised state. Textbooks have been rewritten and new research fields have been established. By reprogramming human cells, scientists have created new opportunities to study diseases and develop methods for diagnosis and therapy.

Life – a journey towards increasing specialisation

All of us developed from fertilized egg cells. During the first days after conception, the embryo consists of immature cells, each of which is capable of developing into all the cell types that form the adult organism. Such cells are called pluripotent stem cells. With further development of the embryo, these cells give rise to nerve cells, muscle cells, liver cells and all other cell types - each of them specialised to carry out a specific task in the adult body. This journey from immature to specialised cell was previously considered to be unidirectional. It was thought that the cell changes in such a way during maturation that it would no longer be possible for it to return to an immature, pluripotent stage.

Frogs jump backwards in development

John B. Gurdon challenged the dogma that the specialised cell is irreversibly committed to its fate. He hypothesised that its genome might still contain all the information needed to drive its development into all the different cell types of an organism. In 1962, he tested this hypothesis by replacing the cell nucleus of a frog's egg cell with a nucleus from a mature, specialised cell derived from the intestine of a tadpole. The egg developed into a fully functional, cloned tadpole and subsequent repeats of the experiment yielded adult frogs. The nucleus of the mature cell had not lost its capacity to drive development to a fully functional organism.

Gurdon's landmark discovery was initially met with scepticism but became accepted when it had been confirmed by other scientists. It initiated intense research and the technique was further developed, leading eventually to the cloning of mammals. Gurdon's research taught us that the nucleus of a mature, specialized cell can be returned to an immature, pluripotent state. But his experiment involved the removal of cell nuclei with pipettes followed by their introduction into other cells. Would it ever be possible to turn an intact cell back into a pluripotent stem cell?

A roundtrip journey – mature cells return to a stem cell state

Shinya Yamanaka was able to answer this question in a scientific breakthrough more than 40 years after Gurdon´s discovery. His research concerned embryonal stem cells, i.e. pluripotent stem cells that are isolated from the embryo and cultured in the laboratory. Such stem cells were initially isolated from mice by Martin Evans (Nobel Prize 2007) and Yamanaka tried to find the genes that kept them immature. When several of these genes had been identified, he tested whether any of them could reprogram mature cells to become pluripotent stem cells.

Yamanaka and his co-workers introduced these genes, in different combinations, into mature cells from connective tissue, fibroblasts, and examined the results under the microscope. They finally found a combination that worked, and the recipe was surprisingly simple. By introducing four genes together, they could reprogram their fibroblasts into immature stem cells!

The resulting induced pluripotent stem cells (iPS cells) could develop into mature cell types such as fibroblasts, nerve cells and gut cells. The discovery that intact, mature cells could be reprogrammed into pluripotent stem cells was published in 2006 and was immediately considered a major breakthrough.

From surprising discovery to medical use

The discoveries of Gurdon and Yamanaka have shown that specialised cells can turn back the developmental clock under certain circumstances. Although their genome undergoes modifications during development, these modifications are not irreversible. We have obtained a new view of the development of cells and organisms.

Research during recent years has shown that iPS cells can give rise to all the different cell types of the body. These discoveries have also provided new tools for scientists around the world and led to remarkable progress in many areas of medicine. iPS cells can also be prepared from human cells.

For instance, skin cells can be obtained from patients with various diseases, reprogrammed, and examined in the laboratory to determine how they differ from cells of healthy individuals. Such cells constitute invaluable tools for understanding disease mechanisms and so provide new opportunities to develop medical therapies.

Sir John B. Gurdon was born in 1933 in Dippenhall, UK. He received his Doctorate from the University of Oxford in 1960 and was a postdoctoral fellow at California Institute of Technology. He joined Cambridge University, UK, in 1972 and has served as Professor of Cell Biology and Master of Magdalene College. Gurdon is currently at the Gurdon Institute in Cambridge.

Shinya Yamanaka was born in Osaka, Japan in 1962. He obtained his MD in 1987 at Kobe University and trained as an orthopaedic surgeon before switching to basic research. Yamanaka received his PhD at Osaka University in 1993, after which he worked at the Gladstone Institute in San Francisco and Nara Institute of Science and Technology in Japan. Yamanaka is currently Professor at Kyoto University and also affiliated with the Gladstone Institute.

Key publications:

Gurdon, J.B. (1962). The developmental capacity of nuclei taken from intestinal epithelium cells of feeding tadpoles. Journal of Embryology and Experimental Morphology 10:622-640.

Takahashi, K., Yamanaka, S. (2006). Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126:663-676.


超人の面白読書 95 ノルウェーのベストセラー作家クナウスゴルドの最新作『Min Kamp』(English title : My Struggle)“わが闘争”の紹介や書評を読む 20







超人の面白読書 95 ノルウェーのベストセラー作家カール・オヴェ・クラウスゴルドの最新作『Min Kamp』(English title : My Struggle)”わが闘争”の紹介や書評を読む 19


« 2012年9月 | トップページ | 2012年11月 »

2 3 4 5 6 7 8
9 10 11 12 13 14 15
16 17 18 19 20 21 22
23 24 25 26 27 28 29
30 31